Hangzhou Tshiab-Test Launches Epoch-ua Tsiaj Diagnostic Cov Khoom Tshiab - Canine thiab Feline Raum Function 3-in-1 combo Test Kit
Hangzhou New-Test Biotechnology Co., Ltd. tau tshaj tawm lub sijhawm tshaj tawm ntawm ob lub sijhawm ua cov khoom kuaj tsiaj tshiab rau lub ntiaj teb cov tsiaj tiv thaiv kab mob kev lag luam: Canine / Feline raum ua haujlwm Triple Test Kit (Creatinine / SDMA / CysC Triple Test) (Daim duab 1 thiab daim duab 2), uas coj cov kev daws teeb meem tshiab thiab meej rau kev kuaj mob thiab kho tsiaj.
Daim duab 1 Canine raum muaj nuj nqi triple test kit Daim duab 2 Feline raum muaj nuj nqi triple test kit
Thaum Lub Kaum Hli 2022, New-Test Biotechnology Co., Ltd. yog thawj zaug tshaj tawm lub ntiaj teb thawj zaug multi-channel multiplex fluorescence immunoassay analyzer, NTIMM4 (tiam thib peb, saib daim duab 3), thiab hauv 2024, tus tshiab single-channel multiplex immunofluorescence analyzer, NTIMM2 (tiam plaub, saib daim duab 4). Qhov tseeb canine / feline raum muaj nuj nqi 3-hauv-1 combo test kit yog sib xws nrog ob qho tib si qauv.
Figure 3 NTIMM4 Figure 4 NTIMM2
Specializing nyob rau hauv me me molecule soj ntsuam kev tshawb fawb thiab kev loj hlob rau rau xyoo, cov khoom tshiab tau launched.
Qhov tseeb ntawm qhov ntsuas me me ntawm cov molecule ib txwm yog qhov nyuaj rau kev kov yeej hauv kev sim POCT, thiab nws tseem yog cov kev taw qhia ntawm kev tshawb fawb thiab kev loj hlob uas Nest-Test Bio tau mob siab rau txij li thaum nws tsim ntau tshaj 6 xyoo dhau los. Lub cev quenching thiab decaying yam ntxwv ntawm tsoos fluorescent cov ntaub ntawv ncaj qha cuam tshuam qhov tseeb ntawm me me molecule nrhiav tau. Tsis tshua muaj-lub ntiaj teb nanocrystal labeling tshuab, lub cim thib plaub ntawm fluorescent nanomaterials tsim los ntawm New-Test, tau lees paub tias yog qhov ruaj khov fluorescent nanomaterials nyob rau hauv kev ua lag luam, uas muaj qhov zoo ntawm kev kov yeej lub cev yam ntxwv ntawm lub teeb quenching. Ua ke nrog ob peb xyoos ntawm kev ua kom zoo ntxiv ntawm cov txheej txheem, nws thaum kawg tau daws qhov teeb meem thoob ntiaj teb ntawm qhov tsis zoo hauv POCT me me molecule kuaj. Thawj thawb yog lub raum ua haujlwm triple kuaj cov khoom siv. Nws lav qhov raug thiab ruaj khov ntawm ob lub me me molecules (creatinine & SDMA) nrhiav kom tau cov tshuaj reagents nyob rau hauv ib lub sij hawm siv tau 2 xyoos.
“Ib qho kev sim no kuj muaj, yog li vim li cas thiaj tsim lub raum ua haujlwm triad” — Keeb kwm ntawm kev loj hlob ntawm lub raum ua haujlwm triad
Tam sim no, cov cim qhia ntawm lub raum tsis zoo hauv cov dev thiab miv suav nrog creatinine (CREA) thiab urea nitrogen hauv biochemistry; CysC (cystatin C) thiab symmetric dimethylarginine (SDMA) hauv kev tiv thaiv kab mob, thiab lwm yam. Tam sim no, feem ntau ntseeg tias tag nrho cov saum toj no - cov ntsuas tau hais los ntawm cov glomerulus. Thaum lub glomerular filtration rate txo qis vim lub raum raug mob, cov ntsuas no yuav ua rau hauv cov ntshav thiab nce siab, yog li qhia txog qib ntawm lub raum - kev ua haujlwm tsis zoo. Lub Koom Haum Thoob Ntiaj Teb rau Kev Tshawb Fawb Txog Kab Mob Raum (IRIS) grading system categorizes lub raum tsis zoo hauv miv rau plaub qib raws li tus nqi ntawm creatinine (Qib I, ib txwm lossis me me: <1.6 mg/dL; Qib II, nruab nrab: 1.6-2.8 mg. /dL; Qib III, hnyav: 2.8-5.0 mg / dL; Qib kawg: > 5.0 mg/dL).
Lub raum tsis zoo hauv cov dev tau muab faib ua plaub qib (Qib I, ib txwm lossis me me: <1.4 mg / dL: Qib II, nruab nrab: 1.4-2.0 mg / dL: Qib III, hnyav: 2.0-4.0 mg / dL: Qib IV, thiab theem kawg: > 4.0 mg/dL). Txawm li cas los xij, vim muaj qhov tsis txaus ntseeg ntawm creatinine hauv cov kab mob raum thaum ntxov (CKD), lwm qhov tseem ceeb tshaj plaws ntawm nephron function filtration, "symmetric dimethylarginine (SDMA)", tau siv. Raws li cov ntaub ntawv, SDMA tuaj yeem pom qhov txawv txav ntawm 25-40% ntawm lub raum tsis zoo, thaum creatinine feem ntau suav tias yog qhov txawv txav ntawm 75% ntawm kev puas tsuaj.
CysC (cystatin C) yog cysteine protease inhibitor, qhov hnyav molecular (13.3 kD), uas tsis yog-glycosylated cov protein. Nws yog ib qho ntawm feem ntau siv cov cim ntawm lub raum ua haujlwm thaum ntxov hauv tib neeg cov tshuaj. Zoo li creatinine thiab SDMA, nws yog lim los ntawm glomerulus, tab sis txawv ntawm creatinine thiab SDMA nyob rau hauv uas nws cov metabolism tsis yog los ntawm cov zis, tab sis yuav luag tag nrho metabolized los ntawm reabsorption los ntawm lub raum tubules. tsis tau pom yav dhau los, ua rau ntau tus kws tshawb fawb, cov kws tshaj lij thiab cov ntawv nyeem rau ob qho kev txiav txim siab txog kev mob raum mob hauv lub raum. miv: qee tus ntseeg tias CysC yog qhov cim ntxov ntawm kev mob raum mob uas tuaj yeem siv tau rau ob leeg dev thiab miv, thaum lwm tus ntseeg tias CysC cuam tshuam me ntsis hauv canine CKD, tab sis tsis zoo hauv miv.
Vim li cas thiaj muaj ob qho lus xaus los ntawm tib "glomerular filtration function index"?
Yog vim li cas yog Anuria, uas yog ib qho mob ntau dua nyob rau hauv miv dua li lwm hom, tshwj xeeb tshaj yog nyob rau hauv txiv neej miv. Qee cov ntaub ntawv qhia tau hais tias qhov tshwm sim ntawm Anuria hauv cov txiv neej miv yog siab li 68.6%, thiab Anuria yuav ncaj qha ua rau muaj kev cuam tshuam ntawm kev tso tawm ntawm creatinine, ntshav urea nitrogen thiab SDMA. Cov kab mob no tas li metabolizing thiab tsim cov creatinine tshiab, ntshav urea nitrogen thiab SDMA, thaum kuaj pom tag nrho peb qhov ntsuas hauv cov ntshav nyob rau lub sijhawm no, yuav muaj qhov nce ntxiv lossis txawm tias tawg ntawm qhov ntsuas txawm tias lub glomerulus puas tiag tiag.
CysC muaj nws tus nqi tshwj xeeb nyob rau lub sijhawm no, txawm hais tias qhov ntsuas no yog glomerular pom, nws tsis yog metabolized los ntawm cov zis, nws yog los ntawm tubular rau reabsorption. Thaum Anuria tshwm sim tab sis lub raum ua haujlwm zoo li qub, CysC Performance index tseem tuaj yeem khaws cia ntawm qib ib txwm muaj. Tsuas yog thaum glomerulus lossis tubular puas tsuaj tiag tiag tshwm sim, CysC Performance index yuav nce mus rau qhov txawv txav. Yog li ntawd, kev tshawb pom ntawm tag nrho peb qhov ntsuas yuav ua rau muaj kev kuaj mob kom raug thiab muab cov kev kho mob sib raug sai thiab ua tau zoo.
Tshiab-Test raum muaj nuj nqi marker 3-hauv-1 kuaj cov khoom muab tshiab qhov tseem ceeb rau kev kuaj pom ntawm lub raum raug mob hauv dev thiab miv!
Piav qhia cov ntsiab lus thiab ua ke nrog cov yam ntxwv ntawm cov ntsuas, New-Test lub raum ua haujlwm cim cim 3-hauv-1 cov khoom siv kuaj tau yug los nrog qhov tseem ceeb ntawm kev kho mob rau dev thiab miv (tshwj xeeb yog miv) nrog Anuria:
Tshiab-Test lub raum muaj nuj nqi marker 3-hauv-1 kuaj cov khoom siv los txiav txim seb puas muaj lub raum ua haujlwm raug mob tiag tiag hauv Anuria mob lossis ua rau muaj qhov nce siab ntawm qhov ntsuas vim tias Anuria. Kev raug mob rau lub raum tiag tiag yuav tsum tsuas yog tso zis catheterization thiab kev saib xyuas ntsig txog, thiab qhov kev kuaj mob feem ntau zoo dua. Qhov kev nce siab ntawm qhov ntsuas ntsuas yuav tsum tsis yog tsuas yog tso zis tso zis thiab kho cov tshuaj tiv thaiv kab mob, tab sis kuj tseem muaj feem cuam tshuam nrog kev kho mob raum, thiab qhov kev tshwm sim muaj teeb meem, thiab nws muaj feem yuav dhau mus ua mob raum mob.
Hauv qab no yog New-Test lub raum ua haujlwm cim 3-hauv-1 cov khoom siv kuaj cov ntaub ntawv rau Anuria ib txwm raug mob (tsis yog lub raum raug mob) thiab Anuria + raum raug mob hauv New-Test soj ntsuam mob:
| Kev tshawb nrhiav Anuria Tshiab-Test raum muaj nuj nqi marker 3-hauv-1 kuaj cov khoom siv | Qhov project | Kev tshwm sim | Kev tshwm sim |
| Creatinine | + | + | |
| SDMA | + | + | |
| CysC | + | - | |
| Xaus | Anuria tau ua rau lub raum raug mob | Thaum ntxov ntawm Anuria thiab lub raum raug mob los yog Anuria uas tseem tsis tau mus txog raum raug mob |
Hauv qab no yog ib feem ntawm cov ntaub ntawv kho mob thiab cov ntaub ntawv piav qhia ntawm New-Test lub raum ua haujlwm 3-hauv-1 cov khoom siv kuaj:
| Cat | Kev Kho Mob Keeb Kwm | Cov tsos mob | CysC (mg / L) | SDHA (ug/dL) | CR (mg / dL) | Xaus |
| 2024090902 | Cystitis / mob raum mob | Kev puas siab puas ntsws tsis zoo, poob qab los noj mov, lub raum tsis zoo, Anuria (Lub raum tsis ua haujlwm, anuria) | 1.09 Nws | 86.47 ib | 8.18 | Lub raum raug mob nrog Anuria |
| 2024091201 | / | Kev puas siab puas ntsws tsis zoo, Anuria, Lub raum ua haujlwm tsis zoo | 0.51 ib | 27.44 Nws | 8.21 ib | Tsis muaj lub raum raug mob nrog Anuria / Thaum Ntxov |
| 2024092702 ib | / | Anuria | 0.31 Nws | > 100.00 | 9.04 ib | Tsis muaj lub raum raug mob nrog Anuria / Thaum Ntxov |
| 2024103101 ib | / | Anuria | 0.3 | 14.11 Nws | 6.52 ib | Tsis muaj lub raum raug mob nrog Anuria / Thaum Ntxov |
| 2024112712 ib | Anuria | 0.5 | > 100.00 | 8.85 ib | Tsis muaj lub raum raug mob nrog Anuria / Thaum Ntxov | |
| 2024112601 | Dysuria / Anuria | 0.43 ib | > 100.00 | 9.06 ib | Tsis muaj lub raum raug mob nrog Anuria / Thaum Ntxov | |
| 0.47 ib | > 100.00 | 878 ib | Tsis muaj lub raum raug mob nrog Anuria / Thaum Ntxov | |||
| 2024112712 ib | / | Anuria | 0.54 ib | 94.03 ib | 8.64 ib | Tsis muaj lub raum raug mob nrog Anuria / Thaum Ntxov |
Hauv cov xwm txheej ntawm Anuria, vim qhov sib txawv ntawm cov txheej txheem hauv metabolic ntawm txhua qhov ntsuas, yuav muaj qhov sib txawv loj rau tib lub raum ua haujlwm pom qhov ntsuas. Yog li ntawd, cov kev faib ua feem ntawm lub raum raug mob ntawm creatinine lossis SDMA yog tsis siv ntxiv lawm, thiab qhov ze tshaj qhov kev soj ntsuam tuaj yeem tsuas yog tau los ntawm kev sib txuas cov kev tshuaj ntsuam nrog lwm qhov ntsuas "CysC". Nws raug pom zoo tias cov chaw soj nstuam (tsev kho mob) tsim cov qauv sab hauv raws li kev paub txog kev kho mob, txhawm rau tshawb nrhiav qhov tseem ceeb ntawm kev kho mob tshiab thiab tshiab.
Thaum kawg, New-Test Biotech vam tias tsab xov xwm no yuav muab pov tseg ib lub cib kom nyiam cov jade, thiab cia siab tias ntau cov kws kho tsiaj hauv Suav teb thiab cov kws tshuaj ntsuam xyuas cov tshuaj reagent yuav tsim cov khoom lag luam tseem ceeb dua thiab pab cov kws kho tsiaj hauv tsev ntau dua kom mus txog qib siab tshaj plaws hauv cov khoom lag luam. ntiaj teb no!
Daim Ntawv Ntxiv: Txais Daim Ntawv Thov Patent rau Kev Tiv Thaiv Kev Txawj Ntse
Post lub sij hawm: Jan-22-2025
