Canine N-terminal B-hom paj hlwb natriuretic peptide precursor yog secreted los ntawm myocardial hlwb nyob rau hauv lub canine ventricle, thiab yuav siv tau raws li ib tug ntsuas qhov ntsuas ntawm lub plawv tsis ua hauj lwm.Qhov concentration ntawm cNT-proBNP nyob rau hauv cov ntshav muaj feem xyuam rau qhov hnyav ntawm tus kab mob.Yog li, NT-proBNP tuaj yeem tsis tsuas yog ntsuas qhov mob hnyav thiab mob plawv tsis ua haujlwm, tab sis kuj yog qhov qhia txog nws qhov kev mob tshwm sim.
Cov khoom no siv fluorescence immunochromatography los kuaj xyuas cov ntsiab lus ntawm cNT-proBNP hauv cov ntshav / ntshav ntau npaum li cas.Lub hauv paus ntsiab lus: Muaj T thiab C kab ntawm nitric acid fiber ntau daim nyias nyias, thiab T kab yog coated nrog cov tshuaj tiv thaiv kab mob uas tshwj xeeb lees paub cNT-proBNP.Cov ntaub ntawv sib xyaw ua ke yog txau nrog lwm cov tshuaj fluorescent nanomaterial uas sau cov tshuaj tiv thaiv kab mob b uas tuaj yeem txheeb xyuas cNT-proBNP.Hauv cov qauv, cNT-proBNP ua ntej ua ke nrog nanomaterial sau npe antibody b los ua ib qho nyuaj, thiab tom qab ntawd mus rau sab sauv chromatography, cov complex ua ke nrog T-line antibody A los ua cov qauv sandwich.Thaum lub
Kev zoo siab ntawm lub teeb irradiation, nanomaterial emits fluorescence signals.Lub zog ntawm lub teeb liab yog qhov zoo sib xws nrog cov concentration ntawm cNT-proBNP hauv cov qauv.
Txij li thaum nws tsim, peb lub Hoobkas tau tsim thawj cov khoom hauv ntiaj teb nrog kev ua raws li txoj cai
ntawm qhov zoo ua ntej.Peb cov khoom tau txais lub koob npe nrov hauv kev lag luam thiab muaj txiaj ntsig zoo ntawm cov neeg siv khoom tshiab thiab qub ..