Feline N-terminal Pro-hlwb Natriuretic Peptide Quantitative Kit (Fluorescent Immunochromatography Assay of Rare Earth Nanocrystals) (fNT-proBNP)

[Product Name]

Lub npe: feline NT-proBNP ib kauj ruam xeem

 

[Packaging Specifications]

10 kev xeem / lub thawv


Product Detail

Khoom cim npe

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Generality

Thaum lub sij hawm tso tawm, cov protein yog cleaved rau lub physiologically active BNP (77th mus rau 108th amino acids) thiab n-terminal fragment NT-proBNP (1st mus rau 76th amino acids).Thaum BNP, uas yog 32 amino acids ntev, yog tso rau hauv cov ntshav, nws khi rau nws cov receptors (NPRA thiab NPRB) thiab tswj cov ntshav siab los ntawm ntau yam mechanisms.NT-proBNP, uas yog 76 amino acids ntev, tsis muaj kev lom zem, tab sis vim tias nws muaj ib nrab-lub neej ntev dua BNP, nws yog qhov tsim nyog tshaj li qhov ntsuas pom ntawm ntau yam kab mob plawv.Hauv kev kuaj mob ntawm cov tsiaj, cov ntshav siab ntawm NT-proBNP hauv dev yog siab dua 900 pmol / L, thiab miv siab dua 270 pmol / L, thiab muaj kev pheej hmoo siab ntawm cov kab mob plawv.Txawm li cas los xij, nws yuav tsum raug sau tseg tias vim tias NT-proBNP raug tso tawm los ntawm lub raum, thaum tus tsiaj raug mob los ntawm cov kab mob hauv lub raum, qhov concentration ntawm NT-proBNP hauv lub cev kuj tseem yuav nce ntxiv thiab qhov tsis zoo yuav tshwm sim ntawm qhov kev sim.

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Detection Principple

Cov khoom no siv fluorescence immunochromatography los kuaj xyuas cov ntsiab lus ntawm fNT-proBNP hauv cov ntshav / ntshav ntau ntau.Lub hauv paus ntsiab lus: Muaj T thiab C kab ntawm nitric acid fiber ntau daim nyias nyias, thiab T kab yog coated nrog cov tshuaj tiv thaiv kab mob uas tshwj xeeb lees paub fNT-proBNP.Cov ntaub ntawv sib xyaw ua ke yog txau nrog lwm cov tshuaj fluorescent nanomaterial sau npe tshuaj tiv thaiv b uas tuaj yeem txheeb xyuas FDT-probNP.Hauv cov qauv, FDT-probNP ua ntej ua ke nrog nanomaterial sau npe antibody b los ua ib qho nyuaj, thiab tom qab ntawd mus rau sab sauv chromatography, cov complex ua ke nrog T-line antibody A los tsim cov qauv sandwich.Thaum lub excitation ntawm lub teeb irradiation, nanomaterial emits fluorescence signals.Lub zog ntawm lub teeb liab yog qhov zoo sib xws nrog cov concentration ntawm fNT-proBNP hauv cov qauv.


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